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2022-8-14 12:36:56

Kuroda Y, Okada A, Shimoda H, Miwa Y, Watamori A,. Influenza A virus infection in domestic ferrets. Jpn J Infect Dis. 2021 Nov 30
submited by kickingbird at Dec, 3, 2021 10:7 AM from Jpn J Infect Dis. 2021 Nov 30

Ferrets are animals that are known to be susceptible to influenza A virus (IAV) infection. To evaluate the risk of IAV transmission from diseased ferrets to humans, we performed a serosurvey to detect specific antibodies against the H1, H3, H5, and H7 subtypes of IAV. We found a high positive rate of the H1 (24.1%) and H3 (5.2%) subtypes in pet ferrets by using an enzyme-linked immunosorbent assay for hemagglutinin proteins. The results were confirmed by the virus-neutralization test for representative antibody-positive serum samples. We also detected hemagglutinin and neuraminidase genes in two ferrets showing acute respiratory illness and whose owner was diagnosed with IAV infection; a human H1N1pdm virus was isolated from one of these ferrets. Our findings suggest that attention should be paid for IAV infection from humans to ferrets, and vice versa.

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