Tsuzuki S, Ishikane M, Matsunaga N, Morioka S, Yu. Interim 2019/2020 influenza vaccine effectiveness in Japan from October 2019 to January 2020. Jpn J Infect Dis. 2020 Sep 30
Herein we report the interim vaccine effectiveness (VE) of quadrivalent inactivated influenza vaccine for the 2019/2020 influenza season in Japan. We conducted a retrospective observational cohort study of 381 enrolled influenza-like illness patients aged ≥ 15 years who were examined via the rapid-influenza diagnostic test at the Ambulatory Care unit of the National Center for Global Health and Medicine in Tokyo, Japan from the beginning of October 2019 to the end of January 2020. VE was estimated using a test-negative design. VE was calculated as (1 - odds ratio) × 100%, comparing influenza A test positivity between vaccinated and unvaccinated patients. Of the 381 patients initially screened for inclusion, 314 were enrolled in the study. Of these, 105 were vaccinated, 98 were diagnosed with influenza A, and 5 were diagnosed with influenza B. Overall VE against influenza A was 27.6% (95% confidence interval [CI] -21.1 to +57.4), and in patients aged ≥ 65 years it was 47.3% (95% CI -76.0 to +86.0). Influenza vaccination can be regarded as being of continued benefit during the ongoing 2019/2020 influenza season, but further accumulation of cases and methodological consideration are necessary to estimate VE more precisely.
See Also:
Latest articles in those days:
- Manganese exposure in juvenile C57BL/6 mice increases glial inflammatory responses in the substantia nigra following infection with H1N1 influenza virus 14 hours ago
- G-quadruplexes in H1N1 influenza genomes 1 days ago
- A broad spectrum HVT-H5 avian influenza vector vaccine which induces a rapid onset of immunity 3 days ago
- In silico prediction of influenza vaccine effectiveness by sequence analysis 3 days ago
- Pathogenicity and transmissibility assessment of two strains of human influenza virus isolated in China in 2018 4 days ago
[Go Top] [Close Window]