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2019-9-21 20:30:44

Wu Y, Gao GF. "Breathing" Hemagglutinin Reveals Cryptic Epitopes for Universal Influenza Vaccine Design. Cell. 2019 May 16;177(5):1086-1088.
submited by kickingbird at May, 20, 2019 14:49 PM from Cell. 2019 May 16;177(5):1086-1088.

A universal vaccine against influenza remains a critical target, and efforts have recently focused on the stem of the hemagglutinin glycoprotein. In this issue of Cell and a related Cell Host & Microbe article, three studies identify broad protective epitopes in the hemagglutinin head domain that are exposed by trimer "breathing."

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