From 10 to 16 April 2026, three new cases of human infection with avian influenza A(H9N2) virus were reported to WHO in the Western Pacific Region. All three cases were children under 10 years of age from China. The first case is a male with comorbidities from Guangdong Province, with symptom onset on 23 February 2026. He was hospitalised with severe pneumonia on 23 February and was discharged on 25 March. The second case is a female from Yunnan Province, with symptom onset on 3 March; the third case is a male from Jiangxi Province, with symptom onset on 20 March. Both cases developed mild symptoms only and did not require hospitalisations. The first and second cases had exposure to poultry, whereas no clear direct poultry exposure was identified for the third case. However, environmental samples from live poultry stalls in the market routinely visited by the family member of the third case tested positive for H9. No additional cases were reported from close contacts of the cases. Since December 2015, a total of 162 cases of human infection with avian influenza A(H9N2), including two deaths (both with underlying conditions), have been reported to WHO in the Western Pacific Region. Of these, 159 were reported from China, two were from Cambodia, and one was from Viet Nam.