General information
Report type: immediate notification
Disease Type: H5N1 
Started: 12 Nov 2021
Confirmed: 18 Nov 2021
Reported: 18 Nov 2021
Reason for notification: recurrence
Species: birds
Causal agent: highly pathogenic avian influenza virus
Disease: highly pathogenic avian influenza (poultry)
Genotype / serotype / subtype: H5N1
Nature of diagnosis: clinical, laboratory
This event pertains to a defined zone within the country.

Summary of outbreak
Total outbreaks: 1
Outbreak locations: Izumi-city1, Himeji-city1
Date of start of the outbreak: 12 Nov 2021
Last occurrence: 30 Jun 2021
Status: ongoing
Affected animals
Species / susceptible / cases / deaths / killed and disposed of /
slaughtered or killed for commercial use / vaccinated /morbidity
(calculated) /mortality (calculated)
Birds - new / 155000 / 70 / 70 / 154930 / 0 / 0 / - / -
Birds - total / 193500 / 93 / 93 / 193407 / 0 / 0 / - / -

Epidemiology
Source of event or origin of infection: unknown or inconclusive
Epidemiological comments:
On 16 Nov 2021, the local veterinary service (Livestock Hygiene
Service Centre; LHSC) in Hyogo Prefecture received a notification from
a domestic laying hen farm of an increase in the number of dead birds.
The samples were collected from dead birds by the LHSC and tested
positive for influenza A virus by antigen-capture kits. On 17 Nov
2021, the LHSC conducted RT-PCR and RRT-PCR tests and confirmed that
the subtype was H5. On 18 Nov 2021, the National Institute of Animal
Health (NIAH) conducted the sequencing test and confirmed that the
subtype of the virus was H5N1 and causative virus was determined as
high pathogenicity avian influenza. Stamping-out policy was applied to
the affected farm. Other control measures (including disinfection)
have been implemented. Movement and shipment restrictions are imposed
on the farms within a radius of 3 km and 3-10 km of the affected farm
respectively. Update for Case1 (Izumi-City1); on 16 Nov 2021 other
control measures (including disinfection) were completed.

Control measures at event level
Domestic control measures applied: ante and post-mortem inspections,
disinfection, movement control inside the country, official disposal
of carcasses, by-products and waste, quarantine, stamping out,
screening, traceability
Wild control measures applied: screening

Diagnostic test results
Test name / category / test type / laboratory / species sampled /
outbreaks / tested from / tested until / result
Real-time reverse transcription polymerase chain reaction (rRT-PCR) /
Nucleic acid detection / Laboratory Test / Livestock Hygiene Service
Centre Local Laboratory / Birds / 2 / 13 Nov 2021 / 17 Nov 21 /
positive
Reverse transcription-polymerase chain reaction (RT-PCR) / Nucleic
acid detection / Laboratory Test / Livestock Hygiene Service Centre
Local Laboratory / Birds / 2 / 13 Nov 2021 / 17 Nov 21 / positive
Gene sequencing / Genotyping / Laboratory Test / The National
Institute of Animal Health National Laboratory / Birds / 2 / 15 Nov
2021 / 18 Nov 21 / positive