Information received on 18/02/2021 from Dr Norio Kumagai, Director, Chief Veterinary Officer, Animal Health Division, Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry and Fisheries, Tokyo, Japan
Summary
Report type
Follow-up report No. 12
Date of start of the event
04/11/2020
Date of confirmation of the event
04/11/2020
Report date
18/02/2021
Date submitted to OIE
18/02/2021
Reason for notification
Recurrence of a listed disease
Date of previous occurrence
14/01/2018
Manifestation of disease
Clinical disease
Causal agent
Highly pathogenic avian influenza virus
Serotype
H5N8
Nature of diagnosis
Clinical, Laboratory (basic), Laboratory (advanced)
This event pertains to
the whole country
Related reports
Immediate notification (06/11/2020)
Follow-up report No. 1 (09/11/2020)
Follow-up report No. 2 (12/11/2020)
Follow-up report No. 3 (18/11/2020)
Follow-up report No. 4 (15/12/2020)
Follow-up report No. 5 (22/12/2020)
Follow-up report No. 6 (25/12/2020)
Follow-up report No. 7 (28/12/2020)
Follow-up report No. 8 (29/12/2020)
Follow-up report No. 9 (04/01/2021)
Follow-up report No. 10 (28/01/2021)
Follow-up report No. 11 (29/01/2021)
Follow-up report No. 12 (18/02/2021)
New outbreaks (9)

Outbreak 1
Sousa-City 2, Chiba
Date of start of the outbreak
03/02/2021
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
176500
13
13
176487
0
Affected population
Poultry(laying hens)
Outbreak 2
Asahi-City 1, Chiba
Date of start of the outbreak
05/02/2021
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
420000
19
19
419981
0
Affected population
Poultry(laying hens)
Outbreak 3
Toko-Town 1, Chiba
Date of start of the outbreak
06/02/2021
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
1150000
6
6
1149994
0
Affected population
Poultry(laying hens)
Outbreak 4
Shintomi-Town 2, Miyazaki
Date of start of the outbreak
06/02/2021
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
240000
32
32
239968
0
Affected population
Poultry(laying hens)
Outbreak 5
Sousa-City 3, Chiba
Date of start of the outbreak
07/02/2021
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
256000
7
7
255993
0
Affected population
Poultry(laying hens)
Outbreak 6
Mima-City 1, Tokushima
Date of start of the outbreak
08/02/2021
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
8000
11
11
7989
0
Affected population
Poultry(broilers)
Outbreak 7
Sousa-City 4, Chiba
Date of start of the outbreak
10/02/2021
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
79000
9
9
78991
0
Affected population
Poultry(laying hens)
Outbreak 8
Sousa-City 5, Chiba
Date of start of the outbreak
10/02/2021
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
278000
36
36
277964
0
Affected population
Poultry(laying hens)
Outbreak 9
Sousa-City 6, Chiba
Date of start of the outbreak
14/02/2021
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
39000
6
6
38994
0
Affected population
Poultry(chicks)
Summary of outbreaks
Total outbreaks: 9
Total animals affected
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
2646500
139
139
2646361
0
Outbreak statistics
Species
Apparent morbidity rate
Apparent mortality rate
Apparent case fatality rate
Proportion susceptible animals lost*
Birds
0.01%
0.01%
100.00%
100.00%
*Removed from the susceptible population through death, destruction and/or slaughter
Epidemiology
Source of the outbreak(s) or origin of infection
Unknown or inconclusive
Epidemiological comments
Follow-up Report No. 12 (Case 42-50) As of the outbreak 1 (Sousa-City 2) in this report (Case 42): On 3rd February 2021, local veterinary service in Chiba Pref. received notification from a layer farm and confirmed influenza A virus by antigen-capture kits. On 4th, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 5th, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. On 7th, stamping-out was completed. An epidemiologically related farm in Asahi-City was identified and all poultry was subjected to preventive culling. On 17th, stamping-out was completed. As of the outbreak 2 (Asahi-City 1) in this report (Case 43): On 5th February 2021, local veterinary service in Chiba Pref. received notification from a layer farm and confirmed influenza A virus by antigen-capture kits. On 6th, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 9th, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. On 14th, stamping-out was completed. As of the outbreak 3 (Tako-Town 1) in this report (Case 44): On 6th February 2021, local veterinary service in Chiba Pref. received notification from a layer farm and confirmed influenza A virus by antigen-capture kits. On 7th, LHSC confirmed H5 by RT-PCR and RRT-PCR. Since 7th, stamping out is being carried out. On 9th, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. As of the outbreak 4 (Shintomi-Town 2) in this report (Case 45): On 6th February 2021, local veterinary service in Miyazaki Pref. received notification from a layer farm and confirmed influenza A virus by antigen-capture kits. On 7th, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 9th, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. On 9th, control measures (stamping out, including disinfection etc) were completed. As of the outbreak 5 (Sousa-City 3) in this report (Case 46): On 7th February 2021, local veterinary service in Chiba Pref. received notification from a layer farm and confirmed influenza A virus by antigen-capture kits. On 8th, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 9th, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. Since 8th, stamping out is being carried out. As of the outbreak 6 (Mima-City 1) in this report (Case 47): On 8th February 2021, local veterinary service in Tokushima Pref. received notification from a broiler farm and confirmed influenza A virus by antigen-capture kits. On 9th, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 10th, control measures (stamping out, including disinfection etc) were completed. On 13th, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. As of the outbreak 7 (Sousa-City 4) in this report (Case 48): On 10th February 2021, local veterinary service in Chiba Pref. received notification from a layer farm and confirmed influenza A virus by antigen-capture kits. On 11th, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 15th, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. On 14th, stamping-out was completed. As of the outbreak 8 (Sousa-City 5) in this report (Case 49): On 10th February 2021, local veterinary service in Chiba Pref. received notification from a layer farm and confirmed influenza A virus by antigen-capture kits. On 11th, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 15th, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. Since 11th, stamping is being carried out. As of the outbreak 9 (Sousa-City 6) in this report (Case 50): On 14th February 2021, local veterinary service in Chiba Pref. received notification from a chick farm and confirmed influenza A virus by antigen-capture kits. On 15th, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 16th, stamping-out was completed. On 17th, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. Movement and shipment restrictions have been imposed on these farms within a radius of 3 km and 3-10 km of the affected farm, respectively.

Control measures
Measures applied
Movement control inside the country
Screening
Quarantine
Stamping out
Disinfection
Vaccination prohibited
No treatment of affected animals
Measures to be applied
No other measures
Diagnostic test results
Laboratory name and type
Species
Test
Test date
Result
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
21/01/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
23/01/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
24/01/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
31/01/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
02/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
04/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
06/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
07/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
07/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
08/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
09/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
11/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
11/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
15/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
21/01/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
23/01/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
24/01/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
31/01/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
02/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
04/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
06/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
07/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
07/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
08/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
09/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
11/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
11/02/2021
Positive
Livestock Hygiene Service (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
15/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
22/01/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
24/01/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
25/01/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
02/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
03/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
05/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
09/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
09/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
09/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
09/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
13/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
13/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
13/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
17/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
22/01/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
24/01/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
25/01/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
02/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
03/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
05/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
09/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
09/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
09/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
09/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
13/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
13/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
13/02/2021
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
17/02/2021
Positive
Future Reporting
The event is continuing. Weekly follow-up reports will be submitted.