Information received on 28/12/2020 from Dr Norio Kumagai, Director, Chief Veterinary Officer, Animal Health Division, Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry and Fisheries, Tokyo, Japan
Summary
Report type
Follow-up report No. 8
Date of start of the event
04/11/2020
Date of confirmation of the event
04/11/2020
Report date
28/12/2020
Date submitted to OIE
28/12/2020
Reason for notification
Recurrence of a listed disease
Date of previous occurrence
14/01/2018
Manifestation of disease
Clinical disease
Causal agent
Highly pathogenic avian influenza virus
Serotype
H5N8
Nature of diagnosis
Clinical, Laboratory (basic), Laboratory (advanced)
This event pertains to
a defined zone within the country
Related reports
Immediate notification (06/11/2020)
Follow-up report No. 1 (09/11/2020)
Follow-up report No. 2 (12/11/2020)
Follow-up report No. 3 (18/11/2020)
Follow-up report No. 4 (15/12/2020)
Follow-up report No. 5 (22/12/2020)
Follow-up report No. 6 (25/12/2020)
Follow-up report No. 7 (28/12/2020)
Follow-up report No. 8 (28/12/2020)
New outbreaks (9)

Outbreak 1
Hyuga-City 2, Miyazaki
Date of start of the outbreak
14/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
46000
60
60
45940
0
Affected population
Poultry(broiler)
Outbreak 2
Kawaminami-Town 1, Miyazaki
Date of start of the outbreak
14/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Slaughterhouse
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
20000

0
20000
0
Affected population
Poultry(broiler)
Outbreak 3
Mitoyo-City 17, Kagawa
Date of start of the outbreak
15/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
15000

0
15000
0
Affected population
Poultry(broiler)
Outbreak 4
Sukumo-City 1, Kochi
Date of start of the outbreak
15/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
27000
40
40
26960
0
Affected population
Poultry(layer)
Outbreak 5
Mitoyo-City 16, Kagawa
Date of start of the outbreak
15/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
14000
34
34
13966
0
Affected population
Poultry(broiler)
Outbreak 6
Miyazaki-City 4, Miyazaki
Date of start of the outbreak
18/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
34000
21
21
33979
0
Affected population
Poultry(broiler parent)
Outbreak 7
Awa-City 1, Tokushima
Date of start of the outbreak
18/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
8000
60
60
7940
0
Affected population
Poultry(layer)
Outbreak 8
Mitoyo-City 18, Kagawa
Date of start of the outbreak
22/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
25000
44
44
24956
0
Affected population
Poultry(broiler)
Outbreak 9
Isumi-City 1, Chiba
Date of start of the outbreak
23/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
1160000
126
126
1159874
0
Affected population
Poultry(layer)
Summary of outbreaks
Total outbreaks: 9
Total animals affected
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
1349000
385 **
385
1348615
0
Outbreak statistics
Species
Apparent morbidity rate
Apparent mortality rate
Apparent case fatality rate
Proportion susceptible animals lost*
Birds
**
0.03%
**
100.00%
*Removed from the susceptible population through death, destruction and/or slaughter
**Not calculated because of missing information
Epidemiology
Source of the outbreak(s) or origin of infection
Unknown or inconclusive
Epidemiological comments
As of the outbreak 1 (Hyuga-City 2) in this report (Case 26): On 14 December 2020, local veterinary service in Miyazaki Pref. received notification from a broiler farm and confirmed influenza A virus by antigen-capture kits. On 14 December 2020, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 15 December, stamping-out and other control measures (including disinfection) were completed. On 17 December, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. There is an epidemiologically related poultry slaughterhouse: the outbreak 2 (Hyuga-City 2) in this report. As of the outbreak 2 (Kawaminami-Town 1) (epidemiologically related poultry slaughterhouse to Case 26): Stamping-out and control measures (including disinfection) were completed on 15 December. As of the outbreak 3 (Sukumo-City 1) in this report (Case 27): On 15 December 2020, local veterinary service in Kochi Pref. received notification from a layer farm and confirmed influenza A virus by antigen-capture kits. On 16 December, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 17 December, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. On 17 December, stamping-out was completed. On 19 December, control measures (including disinfection) were completed. As of the outbreak 4 (Mitoyo-City 16) in this report (Case 28): On 15 December 2020, local veterinary service in Kagawa Pref. received notification from a broiler farm and confirmed influenza A virus by antigen-capture kits. On 16 December, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 17 December, stamping-out was completed. On 19 December, control measures (including disinfection) were completed. On 21 December, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. There is an epidemiologically related farm: the outbreak 5 (Mitoyo-City 17) in this report. As of the outbreak 5 (Mitoyo-City 17) (epidemiologically related farm to Case 28): Stamping-out and other control measures (including disinfection) were completed on 17 and 19 December, respectively. As of the outbreak 6 (Awa-City 1) in this report (Case 29): On 18 December 2020, local veterinary service in Tokushima Pref. received notification from a layer farm and confirmed influenza A virus by antigen-capture kits. On 14 December, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 19 December, stamping-out was completed. On 20 December, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. On 21 December, control measures (including disinfection) were completed. As of the outbreak 7 (Miyazaki-City 4) in this report(Case 30): On 18 December 2020, local veterinary service in Miyazaki Pref. received notification from a broiler parent farm and confirmed influenza A virus by antigen-capture kits. On 19 December, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 20 December, stamping-out and control measures (including disinfection) were completed. On 21 December, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. Movement and shipment restrictions have been imposed on these farms within a radius of 3 km and 3-10 km of the affected farm, respectively.

Control measures
Measures applied
Movement control inside the country
Screening
Quarantine
Stamping out
Disinfection
Vaccination prohibited
No treatment of affected animals
Measures to be applied
No other measures
Diagnostic test results
Laboratory name and type
Species
Test
Test date
Result
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
14/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
14/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
16/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
16/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
16/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
18/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
19/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
23/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
24/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
14/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
14/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
16/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
16/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
16/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
18/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
19/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
23/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
24/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
17/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
17/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
17/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
20/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
21/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
21/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
21/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
25/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
25/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
17/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
17/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
17/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
20/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
21/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
21/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
21/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
25/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
25/12/2020
Positive
Future Reporting
The event is continuing. Weekly follow-up reports will be submitted.