Information received on 25/12/2020 from Dr Norio Kumagai, Director, Chief Veterinary Officer, Animal Health Division, Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry and Fisheries, Tokyo, Japan
Summary
Report type
Follow-up report No. 6
Date of start of the event
04/11/2020
Date of confirmation of the event
04/11/2020
Report date
25/12/2020
Date submitted to OIE
25/12/2020
Reason for notification
Recurrence of a listed disease
Date of previous occurrence
14/01/2018
Manifestation of disease
Clinical disease
Causal agent
Highly pathogenic avian influenza virus
Serotype
H5N8
Nature of diagnosis
Clinical, Laboratory (basic), Laboratory (advanced)
This event pertains to
a defined zone within the country
Related reports
Immediate notification (06/11/2020)
Follow-up report No. 1 (09/11/2020)
Follow-up report No. 2 (12/11/2020)
Follow-up report No. 3 (18/11/2020)
Follow-up report No. 4 (15/12/2020)
Follow-up report No. 5 (22/12/2020)
Follow-up report No. 6 (25/12/2020)
Follow-up report No. 7 (28/12/2020)
Follow-up report No. 8 (28/12/2020)
New outbreaks (8)

Outbreak 1
Gojo-City 1, Nara
Date of start of the outbreak
05/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
77000
30
30
76970
0
Affected population
Poultry(laying hens)
Outbreak 2
Mihara-City 1, Hiroshima
Date of start of the outbreak
06/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
84000
10
10
83990
0
Affected population
Poultry(laying hens)
Outbreak 3
Miyakonojo-City 2, Miyazaki
Date of start of the outbreak
07/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
60000
10
0
60000
0
Affected population
Poultry(broiler)
Outbreak 4
Kobayashi-City 1, Miyazaki
Date of start of the outbreak
07/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
43000
20
20
42980
0
Affected population
Poultry(broiler)
Outbreak 5
Mihara-City 2, Hiroshima
Date of start of the outbreak
07/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
53000

0
53000
0
Affected population
Poultry(laying hens)
Outbreak 6
Saeki-City 1, Oita
Date of start of the outbreak
09/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
14000
33
33
13967
0
Affected population
Poultry(broiler)
Outbreak 7
Saeki-City 2, Oita
Date of start of the outbreak
10/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
24000

0
24000
0
Affected population
Poultry (broiler)
Outbreak 8
Saeki-City 3, Oita
Date of start of the outbreak
10/12/2020
Outbreak status
Continuing (or date resolved not provided)
Epidemiological unit
Farm
Affected animals
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
18000

0
18000
0
Affected population
Poultry(broiler)
Summary of outbreaks
Total outbreaks: 8
Total animals affected
Species
Susceptible
Cases
Deaths
Killed and disposed of
Slaughtered
Birds
373000
103 **
93
372907
0
Outbreak statistics
Species
Apparent morbidity rate
Apparent mortality rate
Apparent case fatality rate
Proportion susceptible animals lost*
Birds
**
0.02%
**
100.00%
*Removed from the susceptible population through death, destruction and/or slaughter
**Not calculated because of missing information
Epidemiology
Source of the outbreak(s) or origin of infection
Unknown or inconclusive
Epidemiological comments
As of the outbreak 1 (Gojo-City 1) in this report (Case 16): On 5 December 2020, local veterinary service in Nara Pref. received notification from a laying hen farm and confirmed influenza A virus by antigen-capture kits. On 6 December 2020, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 7 December, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. On 7 December, stamping-out was completed. On 11 December, control measures (including disinfection) were completed. As of the outbreak 2 (Mihara-City 1) in this report (Case 17): On 6 December 2020, local veterinary service in Hiroshima Pref. received notification from a laying hen farm and confirmed influenza A virus by antigen-capture kits. On 7 December, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 8 December, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. On 9 December, stamping-out was completed. On 17 December, control measures (including disinfection) were completed. There is an epidemiologically related farm: the outbreak 3 (Mihara-City 2) in this report. As of the outbreak 3(Mihara-City 2) in this report (epidemiologically related farm to Case 17): Stamping-out and other control measures (including disinfection) were completed on 9 and 17 December, respectively. As of the outbreak 4 (Miyakonojo-City 2) in this report (Case 18): On 7 December 2020, local veterinary service in Miyazaki Pref. conducted pre-shipment inspection at a broiler farm and confirmed influenza A virus by antigen-capture kits. LHSC confirmed H5 by RT-PCR and RRT-PCR. On 8 December, stamping-out and other control measures (including disinfection) were completed. On 9 December, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. As of the outbreak 5 (Kobayashi-City 1) in this report (Case 19): On 7 December 2020, local veterinary service in Miyazaki Pref. received notification from a broiler farm and confirmed influenza A virus by antigen-capture kits. On 8 December, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 8 December, stamping-out and other control measures (including disinfection) completed. On 9 December, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. As of the outbreak 6 (Saeki-City 1) in this report (Case 20): On 9 December 2020, local veterinary service in Oita Pref. received notification from a broiler farm and confirmed influenza A virus by antigen-capture kits. On 10 December, LHSC confirmed H5 by RT-PCR and RRT-PCR. On 11 December, NIAH confirmed H5N8 HPAI by RT-PCR and sequencing. On 10 December, stamping-out and control measures (including disinfection) were completed. There are epidemiologically related farms; the outbreak 7 (Saeki-City 2) and 8 (Saeki-City 3) in this report. As of the outbreak 7 (Saeki-City 2) in this report (epidemiologically related farm to Case 20): Stamping-out and other control measures (including disinfection) were completed on 11 December, respectively. As of the outbreak 8 (Saeki-City 3) in this report (epidemiologically related farm to Case 20): Stamping-out and other control measures (including disinfection) were completed on 11 December, respectively. Movement and shipment restrictions have been imposed on there farms within a radius of 3 km and 3-10 km of the affected farm, respectively.

Control measures
Measures applied
Movement control inside the country
Screening
Quarantine
Stamping out
Disinfection
Vaccination prohibited
No treatment of affected animals
Measures to be applied
No other measures
Diagnostic test results
Laboratory name and type
Species
Test
Test date
Result
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
06/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
07/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
07/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
08/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
real-time reverse transcriptase/polymerase chain reaction (RRT-PCR)
10/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
06/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
07/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
07/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
08/12/2020
Positive
Livestock Hygiene Service Centre (Local laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
10/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
07/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
09/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
09/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
09/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
gene sequencing
11/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
07/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
09/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
09/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
09/12/2020
Positive
National Institute of Animal Health (National laboratory)
Birds
reverse transcription - polymerase chain reaction (RT-PCR)
11/12/2020
Positive
Future Reporting
The event is continuing. Weekly follow-up reports will be submitted.