WHO: Status of candidate vaccine virus development for the current Influenza A(H1N1) virus

Publication date: 8 May 2009

For the current influenza A(H1N1) virus, WHO Collaborating Centres for influenza (WHO CCs), Essential Regulatory Laboratories (ERLs) and other institutions are developing candidate vaccine viruses under the coordination of WHO1. Once a vaccine virus is available, WHO will announce the availability on its public website2. For general queries, please email to GISN@who.int

Candidate vaccine viruses using reverse genetics technology are being developed by:

Candidate vaccine viruses using classical reassortment technology are being developed by:

Development of vaccine potency reagents for inactivated vaccines against Influenza A(H1N1) is planned in:

Wild type viruses have been/ are being sent to vaccine manufacturers on request including:

Baxter, CSL Limited, GlaxoSmithKline Biologicals, MedImmune, Microgen, Nobilon International, Novartis, Omninvest Vaccines, Pasteur, Solvay and Vivaldi.

1 WHO coordinates WHO CCs, National Influenza Centers and ERLs. This Network is monitoring the evolution of influenza viruses, both seasonal and those with potential to cause a pandemic, including the current influenza A(H1N1). The Network also provides recommendations and updates on diagnostics, monitors the susceptibility of emerging influenza viruses to antiviral drugs, and selects, develops and distributes vaccine viruses.
2 http://www.who.int/csr/disease/swineflu/en/index.html