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2024-3-28 22:14:45
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Baumann J, Mounogou Kouassi N, Foni E, Klenk HD, e. H1N1 Swine Influenza Viruses Differ from Avian Precursors by a higher pH Optimum of Membrane Fusion. J Virol 2015 Nov 25. pii: JVI.02332..  Abstract  
submitted by kickingbird at Dec, 1, 2015 from J Virol 2015 Nov 25. pii: JVI.02332. (via http://www.ncbi.nlm.nih.gov/m/pubmed/26608319/)
The H1N1 Eurasian avian-like swine (EAsw) influenza viruses originated from an avian H1N1 virus. To characterize potential changes in the membrane fusion activity of the HA during avian-to-swine adaptation ...

Schulert GS, Zhang M, Fall N, Husami A, et al. Whole exome sequencing reveals mutations in hemophagocytic lymphohistiocytosis and macrophage activation syndrome linked genes in fatal cases of H1N1 influenza. J Infect Dis 2015..  Abstract  
submitted by kickingbird at Dec, 1, 2015 from J Infect Dis 2015. (via http://www.ncbi.nlm.nih.gov/m/pubmed/26597256/)
BACKGROUND: ?Severe H1N1 influenza can be lethal in otherwise healthy individuals, and have features of secondary hemophagocytic lymphohistiocytosis (HLH). HLH is associated with mutations in lymphocyte ...

Fang CF, Ma MJ, Zhan BD, Lai SM, et al.. Nosocomial transmission of avian influenza A (H7N9) virus in China: epidemiological investigation. BMJ 2015;351:h5765.  Abstract  
submitted by kickingbird at Dec, 1, 2015 from BMJ 2015;351:h5765 (via http://www.ncbi.nlm.nih.gov/m/pubmed/26586515)
STUDY QUESTION: Can avian influenza A (H7N9) virus be transmitted between unrelated individuals in a hospital setting? METHODS: An epidemiological investigation looked at two patients who shared a hospital ...

Yuan S, Chu H, Zhao H, Zhang K, et al. Identification of a small-molecule inhibitor of influenza virus via disrupting the subunits interaction of the viral polymerase. Antiviral Res 2015 Nov 21. pii: S0166-3542(15)3002.  Abstract  
submitted by kickingbird at Dec, 1, 2015 from Antiviral Res 2015 Nov 21. pii: S0166-3542(15)3002 (via http://www.ncbi.nlm.nih.gov/m/pubmed/26593979/)
Assembly of the heterotrimeric influenza virus polymerase complex from the individual subunits PB1, PA, and PB2 is a prerequisite for viral replication, in which the interaction between the C terminal ...

LI Zhaowei, etc.,al. Epidemiological surveys of H9N2 subtype avian influenza in live bird markets in the regions of the Yangtze RiverDelta and Pearl River Delta in China. Animal Husbandry & Veterinary Medicine 2015 Vol. 4.  Abstract  
submitted by kickingbird at Nov, 10, 2015 from Animal Husbandry & Veterinary Medicine 2015 Vol. 4 (via http://www.cnki.net)
Abstract: To investigate the circulation and replication of H9N2 subtype avian influenza viruses ( AIVs) in live bird markets ( LBMs) inChina,a total of 12 635 swab samples were collected from 58 randomly ...

KONG Dong-feng, etc.,al. Epidemiological characteristics and control measures of influenza A(H1N1) in Shenzhen City from 2009 to 2013. Occup and Health, Oct. 2015,Vol. 31, No.19.  Abstract  
submitted by kickingbird at Nov, 10, 2015 from Occup and Health, Oct. 2015,Vol. 31, No.19 (via http://www.cnki.net)
Abstract:[Objective]To analyze epidemiological characteristics of influenza A( H1N1) in Shenzhen City from 2009-2013, providescientific evidence for control and prevention of influenza pandemic in future. ...

OTHUMPANGAT S, Noti JD, McMillen CM, Beezhold DH,. ICAM-1 regulates the survival of influenza virus in lung epithelial cells during the early stages of infection. Virology. 2015 Oct 22;.  Abstract  
submitted by kickingbird at Nov, 2, 2015 from Virology. 2015 Oct 22; (via http://www.ncbi.nlm.nih.gov/pubmed/26499045)
Intercellular cell adhesion molecule-1 (ICAM-1) is an inducible cell surface glycoprotein that is expressed on many cell types. Influenza virus infection enhanced ICAM-1 expression and messenger RNA levels. ...

WOHLBOLD TJ, Chromikova V, Tan GS, Meade P, et al. Hemagglutinin stalk- and neuraminidase-specific monoclonal antibodies protect against lethal H10N8 influenza virus infection in mice. J Virol. 2015 Oct 28.  Abstract  
submitted by kickingbird at Nov, 2, 2015 from J Virol. 2015 Oct 28 (via http://www.ncbi.nlm.nih.gov/pubmed/26512088)
Between November 2013 and February 2014, China reported three human cases of H10N8 influenza virus infection in the Jiangxi province, two of which were fatal. Using hybridoma technology, we isolated a ...

HU Y, Jiang L, Lai W, Qin Y, et al. MiR-33a disturbs influenza A virus replication via targeting ARCN1 and inhibiting viral vRNP activity. J Gen Virol. 2015 Oct 22..  Abstract  
submitted by kickingbird at Nov, 2, 2015 from J Gen Virol. 2015 Oct 22. (via http://www.ncbi.nlm.nih.gov/pubmed/26498766)
In order to explore the roles of miRNA(s) involved influenza A virus life cycle, we compared the miRNA profiles of HEK293 and HeLa cell lines, since influenza A virus can replicate efficiently in HEK293cells ...

HERVE PL, Lorin V, Jouvion G, Da Costa B, et al. Addition of N-glycosylation sites on the globular head of the H5 hemagglutinin induces the escape of highly pathogenic avian influenza A H5N1 viruses from vaccine-induced immunity. Virology. 2015 Sep 30;486:134-145. doi: 10.1016/.  Abstract  
submitted by kickingbird at Oct, 13, 2015 from Virology. 2015 Sep 30;486:134-145. doi: 10.1016/ (via http://www.ncbi.nlm.nih.gov/pubmed/26433051)
Highly pathogenic avian influenza A H5N1 viruses remain endemic in poultry in several countries and still constitute a pandemic threat. Since the early 20th century, we experienced four influenza A pandemics. ...

PILLET S, Racine T, Nfon C, Di Lenardo TZ, et al. Plant-derived H7 VLP vaccine elicits protective immune response against H7N9 influenza virus in mice and ferrets. Vaccine. 2015 Sep 30. pii: S0264-410X(15)01341-9..  Abstract  
submitted by kickingbird at Oct, 13, 2015 from Vaccine. 2015 Sep 30. pii: S0264-410X(15)01341-9. (via http://www.ncbi.nlm.nih.gov/pubmed/26432915)
In March 2013, the Chinese Centre for Disease Control and Prevention confirmed the first reported case of human infection with an avian influenza A H7N9 virus. Infection with this virus often caused severe ...

ANCHISI S, Guerra J, Mottet-Osman G, Garcin D, et. Mismatches in Influenza A virus vRNA panhandle prevent RIG-I sensing by impairing RNA/RIG-I complex formation. J Virol. 2015 Oct 7. pii: JVI.01671-15..  Abstract  
submitted by kickingbird at Oct, 13, 2015 from J Virol. 2015 Oct 7. pii: JVI.01671-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26446607)
Influenza virus RNA promoter panhandle structures are believed to be sensed by RIG-I. The occurrence of mismatches in this dsRNA structure raises questions about their effect on innate sensing. Our results ...

PICHYANGKUL S, Yongvanitchit K, Limsalakpetch A, K. Tissue Distribution of Memory T and B Cells in Rhesus Monkeys following Influenza A Infection. J Immunol. 2015 Sep 25..  Abstract  
submitted by kickingbird at Oct, 9, 2015 from J Immunol. 2015 Sep 25. (via http://www.ncbi.nlm.nih.gov/pubmed/26408671)
Studies of influenza-specific immune responses in humans have largely assessed systemic responses involving serum Ab and peripheral blood T cell responses. However, recent evidence indicates that tissue-resident ...

FERGUSON L, Eckard L, Epperson WB, Long LP, et al. Influenza D virus infection in Mississippi beef cattle. Virology. 2015 Sep 16;486:28-34. doi:.  Abstract  
submitted by kickingbird at Sep, 27, 2015 from Virology. 2015 Sep 16;486:28-34. doi: (via http://www.ncbi.nlm.nih.gov/pubmed/26386554)
A new member of the Orthomyxoviridae family, influenza D virus (IDV), was first reported in swine in the Midwest region of the United States. This study aims to extend our knowledge on the IDV epidemiology ...

FULTON BO, Palese P, Heaton NS. Replication competent influenza B reporter viruses as tools for screening antivirals and antibodies. J Virol. 2015 Sep 23..  Abstract  
submitted by kickingbird at Sep, 27, 2015 from J Virol. 2015 Sep 23. (via http://www.ncbi.nlm.nih.gov/pubmed/26401044)
Influenza B virus is a human pathogen responsible for significant health and economic burden. Research into this pathogen has been limited by the lack of reporter viruses. Here we describe the development ...

OKUYA K, Kawabata T, Nagano K, Tsukiyama-Kohara K,. Isolation and characterization of influenza A viruses from environmental water at an overwintering site of migratory birds in Japan. Arch Virol. 2015 Sep 21..  Abstract  
submitted by kickingbird at Sep, 27, 2015 from Arch Virol. 2015 Sep 21. (via http://www.ncbi.nlm.nih.gov/pubmed/26392284)
The Izumi plain in Kagoshima prefecture, Japan, is an overwintering site of more than 10,000 cranes. The wet paddy areas are artificially created to provide roosting sites for the cranes every winter. ...

VAN POUCKE S, Doedt J, Baumann J, Qiu Y, et al. Role of Substitutions in the Hemagglutinin in the Emergence of the 1968 Pandemic Influenza Virus. J Virol. 2015 Sep 16. pii: JVI.01292-15..  Abstract  
submitted by kickingbird at Sep, 21, 2015 from J Virol. 2015 Sep 16. pii: JVI.01292-15. (via http://www.ncbi.nlm.nih.gov/pubmed/26378170)
Hemagglutinin (HA) of H3N2/1968 pandemic influenza viruses differed from putative avian precursor by seven amino acid substitutions. Substitutions Q226L and G228S are known to be essential for avian-to-mammalian ...

TRAVANTY E, Zhou B, Zhang H, Di YP, et al. Differential susceptibility of human lung primary cells to H1N1 influenza viruses. J Virol. 2015 Sep 16..  Abstract  
submitted by kickingbird at Sep, 21, 2015 from J Virol. 2015 Sep 16. (via http://www.ncbi.nlm.nih.gov/pubmed/26378172)
Human alveolar epithelial cells (AECs) and alveolar macrophages (AMs) are the first lines of lung defense. In this study we report that AECs are the direct targets for H1N1 viruses that have circulated ...

TAYLOR G, Abdesselam K, Pelude L, Fernandes R, et. Epidemiological features of influenza in Canadian adult intensive care unit patients. Epidemiol Infect. 2015 Sep 18:1-10..  Abstract  
submitted by kickingbird at Sep, 21, 2015 from Epidemiol Infect. 2015 Sep 18:1-10. (via http://www.ncbi.nlm.nih.gov/pubmed/26384310)
To identify predictive factors and mortality of patients with influenza admitted to intensive care units (ICU) we carried out a prospective cohort study of patients hospitalized with laboratory-confirmed ...

LEI H, Peng X, Zhao D, Jiao H, et al. Cross-protection of Lactococcus lactis-displayed HA2 subunit against homologous and heterologous influenza A viruses in mice. Arch Virol. 2015 Sep 11.  Abstract  
submitted by kickingbird at Sep, 21, 2015 from Arch Virol. 2015 Sep 11 (via http://www.ncbi.nlm.nih.gov/pubmed/26358264)
Current influenza vaccines provide strain-specific protection against homologous subtypes and need to be updated annually. Therefore, it is essential to develop a universal vaccine that would induce broadly ...

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