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2024-3-28 19:12:30
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Wen F, Yan Z, Chen G, Chen Y, Wang N, Li Z, Guo J,. Recent H9N2 avian influenza virus lost hemagglutination activity due to a K141N substitution in hemagglutinin. J Virol. 2024 Mar 11:e0024824.  Abstract  
submitted by kickingbird at Mar, 12, 2024 from J Virol. 2024 Mar 11:e0024824 (via https://journals.asm.org/doi/10.1128/jvi.00248-24)
The H9N2 avian influenza virus (AIV) represents a significant risk to both the poultry industry and public health. Our surveillance efforts in China have revealed a growing trend of recent H9N2 AIV strains ...

Plaza PI, Gamarra-Toledo V, Rodríguez Euguí J, Ros. Pacific and Atlantic sea lion mortality caused by highly pathogenic Avian Influenza A(H5N1) in South America. Travel Med Infect Dis. 2024 Mar 8:102712.  Abstract  
submitted by kickingbird at Mar, 11, 2024 from Travel Med Infect Dis. 2024 Mar 8:102712 (via https://www.sciencedirect.com/science/article/pii/S147789392)
We describe the evolution of the outbreak of Highly Pathogenic Avian Influenza (HPAI) A(H5N1) in sea lions (Otaria flavescens) of South America. At least 24,000 sea lions died in Peru, Chile, Argentina, ...

Koutsakos M, Rockman S, Krammer F. Is eradication of influenza B viruses possible?. Lancet Infect Dis. 2024 Mar 4:S1473-3099(24)00132-.  Abstract  
submitted by kickingbird at Mar, 10, 2024 from Lancet Infect Dis. 2024 Mar 4:S1473-3099(24)00132- (via https://www.thelancet.com/journals/laninf/article/PIIS1473-3)
Influenza B virus infections account for a substantial proportion of cases of influenza annually, with a high morbidity and mortality burden, especially in children (aged 0–18 years). Influenza B virus, ...

Kim JY, Jeong S, Kim DW, Lee DW, Lee DH, Kim D, Kw. Genomic epidemiology of highly pathogenic avian influenza A (H5N1) virus in wild birds in South Korea during 2021-2022: Changes in viral epidemic patterns. Virus Evol. 2024 Feb 7;10(1):veae014..  Abstract  
submitted by kickingbird at Mar, 10, 2024 from Virus Evol. 2024 Feb 7;10(1):veae014. (via https://academic.oup.com/ve/article/10/1/veae014/7606456)
Clade 2.3.4.4b highly pathogenic avian influenza A (HPAI) viruses have been detected in wild birds worldwide, causing recurrent outbreaks since 2016. During the winter of 2021-2022, we detected one H5N8 ...

Mao Q, Li Z, Li Y, Zhang Y, Liu S, Yin X, Peng C,. H5N1 high pathogenicity avian influenza virus in migratory birds exhibiting low pathogenicity in mallards increases its risk of transmission and spread in poultry. Vet Microbiol. 2024 Mar 2;292:110038.  Abstract  
submitted by kickingbird at Mar, 10, 2024 from Vet Microbiol. 2024 Mar 2;292:110038 (via https://www.sciencedirect.com/science/article/abs/pii/S03781)
In 2020, an H5N1 avian influenza virus of clade 2.3.4.4b was detected in Europe for the first time and was spread throughout the world by wild migratory birds, resulting in the culling of an unprecedented ...

Lim WW, Shuo F, Wong SS, Sullivan SG, Cowling BJ. Hemagglutination inhibition antibody titers mediate influenza vaccine efficacy against symptomatic influenza A(H1N1), A(H3N2), and B/Victoria infections. J Infect Dis. 2024 Mar 7:jiae122.  Abstract  
submitted by kickingbird at Mar, 8, 2024 from J Infect Dis. 2024 Mar 7:jiae122 (via https://academic.oup.com/jid/advance-article-abstract/doi/10)
Background: The hemagglutination inhibition antibody (HAI) titer mediates only a part of vaccine-induced protection against influenza virus infections. Using causal mediation analysis, we quantified the ...

Tapia R, Brito B, Saavedra M, Mena J, García-Salum. Novel influenza A viruses in pigs with zoonotic potential, Chile. Microbiol Spectr. 2024 Mar 6:e0218123.  Abstract  
submitted by kickingbird at Mar, 7, 2024 from Microbiol Spectr. 2024 Mar 6:e0218123 (via https://journals.asm.org/doi/10.1128/spectrum.02181-23)
Novel H1N2 and H3N2 swine influenza A viruses (IAVs) have recently been identified in Chile. The objective of this study was to evaluate their zoonotic potential. We perform phylogenetic analyses to determine ...

Tan M, Zhang Y, Bo H, Li X, Zou S, Yang L, Liu J,. Rapid adaptive substitution of L226Q in HA protein increases the pathogenicity of H9N2 viruses in mice. Infect Med (Beijing). 2024 Feb 13;3(1):100090.  Abstract  
submitted by kickingbird at Mar, 7, 2024 from Infect Med (Beijing). 2024 Feb 13;3(1):100090 (via https://www.sciencedirect.com/science/article/pii/S2772431X2)
Background: Since the first human infection with H9N2 virus was reported in 1998, the number of cases of H9N2 infection has exceeded one hundred by 2021. However, there is no systematic description of ...

Sanogo IN, Guinat C, Dellicour S, Diakité MA, Nian. Genetic insights of H9N2 avian influenza viruses circulating in Mali and phylogeographic patterns in Northern and Western Africa. Virus Evol. 2024 Feb 19;10(1):veae011.  Abstract  
submitted by kickingbird at Mar, 6, 2024 from Virus Evol. 2024 Feb 19;10(1):veae011 (via https://academic.oup.com/ve/article/10/1/veae011/7610485)
Avian influenza viruses (AIVs) of the H9N2 subtype have become widespread in Western Africa since their first detection in 2017 in Burkina Faso. However, the genetic characteristics and diffusion patterns ...

Aracena KA, Lin YL, Luo K, Pacis A, Gona S, Mu Z,. Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Nat Genet. 2024 Feb 29.  Abstract  
submitted by kickingbird at Mar, 3, 2024 from Nat Genet. 2024 Feb 29 (via https://www.nature.com/articles/s41588-024-01668-z)
Humans display remarkable interindividual variation in their immune response to identical challenges. Yet, our understanding of the genetic and epigenetic factors contributing to such variation remains ...

Frutos AM, Price AM, Harker E, Reeves EL, Ahmad HM. Interim Estimates of 2023-24 Seasonal Influenza Vaccine Effectiveness - United States. MMWR Morb Mortal Wkly Rep. 2024 Feb 29;73(8):168-1.  Abstract  
submitted by kickingbird at Mar, 1, 2024 from MMWR Morb Mortal Wkly Rep. 2024 Feb 29;73(8):168-1 (via https://www.cdc.gov/mmwr/volumes/73/wr/mm7308a3.htm?s_cid=mm)
In the United States, annual influenza vaccination is recommended for all persons aged ≥6 months. Using data from four vaccine effectiveness (VE) networks during the 2023-24 influenza season, interim influenza ...

Monjane IVA, Djedje H, Tamele E, Nhabomba V, Tivan. H7N6 highly pathogenic avian influenza in Mozambique, 2023. Emerg Microbes Infect. 2024 Dec;13(1):2321993.  Abstract  
submitted by kickingbird at Mar, 1, 2024 from Emerg Microbes Infect. 2024 Dec;13(1):2321993 (via https://www.tandfonline.com/doi/full/10.1080/22221751.2024.2)
On 13 October 2023, the National Directorate for Livestock Development in Mozambique was notified of a suspected outbreak of avian influenza in commercial layers. Samples were screened by real-time and ...

Ding X, Liu J, Jiang T, Wu A. Transmission restriction and genomic evolution co-shape the genetic diversity patterns of influenza A virus. Virol Sin. 2024 Feb 27:S1995-820X(24)00025-7.  Abstract  
submitted by kickingbird at Mar, 1, 2024 from Virol Sin. 2024 Feb 27:S1995-820X(24)00025-7 (via https://www.sciencedirect.com/science/article/pii/S1995820X2)
Influenza A virus (IAV) shows an extensive host range and rapid genomic variations, leading to continuous emergence of novel viruses with significant antigenic variations and the potential for cross-species ...

Zhang M, Liu M, Chen H, Qiu T, Jin X, Fu W, Teng Q. PB2 residue 473 contributes to the mammalian virulence of H7N9 avian influenza virus by modulating viral polymerase activity via ANP32A. J Virol. 2024 Feb 29:e0194423.  Abstract  
submitted by kickingbird at Mar, 1, 2024 from J Virol. 2024 Feb 29:e0194423 (via https://journals.asm.org/doi/10.1128/jvi.01944-23)
Since the first human infection reported in 2013, H7N9 avian influenza virus (AIV) has been regarded as a serious threat to human health. In this study, we sought to identify the virulence determinant ...

Yang R, Pan M, Guo J, Huang Y, Zhang QC, Deng T, W. Mapping of the influenza A virus genome RNA structure and interactions reveals essential elements of viral replication. Cell Rep. 2024 Feb 27;43(3):113833.  Abstract  
submitted by kickingbird at Feb, 29, 2024 from Cell Rep. 2024 Feb 27;43(3):113833 (via https://www.cell.com/cell-reports/fulltext/S2211-1247(24)001)
Influenza A virus (IAV) represents a constant public health threat. The single-stranded, segmented RNA genome of IAV is replicated in host cell nuclei as a series of 8 ribonucleoprotein complexes (vRNPs) ...

Han J, Chang W, Fang J, Hou X, Li Z, Wang J, Deng. The H9N2 avian influenza virus increases APEC adhesion to oviduct epithelia by viral NS1 protein-mediated activation of the TGF-β pathway. J Virol. 2024 Feb 28:e0151223.  Abstract  
submitted by kickingbird at Feb, 29, 2024 from J Virol. 2024 Feb 28:e0151223 (via https://journals.asm.org/doi/10.1128/jvi.01512-23)
Avian influenza A (H9N2) avian influenza is a low-pathogenic avian influenza circulating in poultry and wild birds worldwide and frequently contributes to chicken salpingitis that is caused by avian pathogenic ...

Cardenas-Garcia S, Cáceres CJ, Jain A, Geiger G, M. Impact of sex on humoral immunity with live influenza B virus vaccines in mice. NPJ Vaccines. 2024 Feb 26;9(1):45.  Abstract  
submitted by kickingbird at Feb, 28, 2024 from NPJ Vaccines. 2024 Feb 26;9(1):45 (via https://www.nature.com/articles/s41541-024-00827-x)
Influenza B virus (FLUBV) poses a significant infectious threat, with frequent vaccine mismatch limiting its effectiveness. Our previous work investigated the safety and efficacy of modified live attenuated ...

de Bruin ACM, Spronken MI, Kok A, Rosu ME, de Meul. Species-specific emergence of H7 highly pathogenic avian influenza virus is driven by intrahost selection differences between chickens and ducks. PLoS Pathog. 2024 Feb 26;20(2):e1011942.  Abstract  
submitted by kickingbird at Feb, 27, 2024 from PLoS Pathog. 2024 Feb 26;20(2):e1011942 (via https://journals.plos.org/plospathogens/article?id=10.1371/j)
Highly pathogenic avian influenza viruses (HPAIVs) cause severe hemorrhagic disease in terrestrial poultry and are a threat to the poultry industry, wild life, and human health. HPAIVs arise from low pathogenic ...

Gu C, Fan S, Dahn R, Babujee L, Chiba S, Guan L, M. Characterization of a human H3N8 influenza virus. EBioMedicine. 2024 Feb 25;101:105034.  Abstract  
submitted by kickingbird at Feb, 27, 2024 from EBioMedicine. 2024 Feb 25;101:105034 (via https://www.thelancet.com/journals/ebiom/article/PIIS2352-39)
Background: In 2022 and 2023, novel reassortant H3N8 influenza viruses infected three people, marking the first human infections with viruses of this subtype.Methods: Here, we generated one of these viruses ...

Rose AMC, Pozo F, Martínez-Baz I, Mazagatos C, Bos. Vaccine effectiveness against influenza hospitalisation in adults during the 2022/2023 mixed season of influenza A(H1N1)pdm09, A(H3N2) and B circulation, Europe: VEBIS SARI VE hospital network. Influenza Other Respir Viruses. 2024 Feb;18(2):e13.  Abstract  
submitted by kickingbird at Feb, 27, 2024 from Influenza Other Respir Viruses. 2024 Feb;18(2):e13 (via https://onlinelibrary.wiley.com/doi/10.1111/irv.13255)
We conducted a multicentre hospital-based test-negative case-control study to measure vaccine effectiveness (VE) against PCR-confirmed influenza in adult patients with severe acute respiratory infection ...

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