Huang QJ, Kim R, Song K, Grigorieff N, Munro JB, S. [preprint]Virion-associated influenza hemagglutinin clusters upon sialic acid binding visualized by cryo-electron tomography. bioRxiv. 2024 Oct 18:2024.10.15.618557. Abstract submitted by kickingbird at 11 hours ago from bioRxiv. 2024 Oct 18:2024.10.15.618557 Influenza viruses are enveloped, negative sense single-stranded RNA viruses covered in a dense layer of glycoproteins. Hemagglutinin (HA) accounts for 80-90% of influenza glycoprotein and plays a role ... Pulit-Penaloza, J.A., Belser, J.A., Brock, N. et a. Transmission of a human isolate of clade 2.3.4.4b A(H5N1) virus in ferrets. Nature (2024). Abstract submitted by kickingbird at 18 hours ago from Nature (2024) Since 2020, there has been unprecedented global spread of highly pathogenic avian influenza A(H5N1) in wild bird populations with spillover into a variety of mammalian species and sporadically humans. ... Gu, C., Maemura, T., Guan, L. et al. A human isolate of bovine H5N1 is transmissible and lethal in animal models. Nature (2024). Abstract submitted by kickingbird at 18 hours ago from Nature (2024) The outbreak of clade 2.3.4.4b highly pathogenic avian influenza viruses of the H5N1 subtype (HPAI H5N1) in dairy cows in the US has so far resulted in spillover infections of at least thirteen farm workers1-3, ... Daidoji T, Sadakane H, Garan K, Kawashita N, Arai. The host tropism of current zoonotic H7N9 viruses depends mainly on an acid-labile hemagglutinin with a single amino acid mutation in the stalk region. PLoS Pathog. 2024 Oct 22;20(10):e1012427. Abstract submitted by kickingbird at 2 days ago from PLoS Pathog. 2024 Oct 22;20(10):e1012427 The incidence of human infection by zoonotic avian influenza viruses, especially H5N1 and H7N9 viruses, has increased. Current zoonotic H7N9 avian influenza viruses (identified since 2013) emerged during ... Heinz Feldmann, etc.,al. [preprint]Orogastric Exposure of Cynomolgus Macaques to Bovine HPAI H5N1 Virus Results in Subclinical Infection. https://doi.org/10.21203/rs.3.rs-5182487/v1. Abstract submitted by kickingbird at 2 days ago from https://doi.org/10.21203/rs.3.rs-5182487/v1 Since early 2022 highly pathogenic avian influenza (HPAI) H5N1 virus infections have been reported in wild aquatic birds and poultry throughout the United States (US) with spillover into several mammalian ... | |